Glia and Inflammation in Neurodegenerative Disease by M.a. Yenari

Glia and Inflammation in Neurodegenerative Disease

M.a. Yenari
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Details

  • ISBN
    9781594549847 / 1594549842
  • Title Glia and Inflammation in Neurodegenerative Disease
  • Author M.a. Yenari
  • Category Immunology
    Neurology & Clinical Neurophysiology
  • Format
    Hardcover
  • Year 2007
  • Pages 275
  • Publisher
    Nova Science Publishers Inc
  • Imprint Nova Science Publishers Inc
  • Edition
    1st
  • Language English
  • Dimensions 260mm x 180mm x 262mm

Annotation

Reviews the knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. This book considers the changing role of inflammation with development. It also presents a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.

Publisher Description

The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brains resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.

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Glia and Inflammation in Neurodegenerative Disease

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