Two groups of students attend Cross Academy. Yuki Cross and Zero Kiryu are the Guardians of the school, protecting the Day Class from the Academy's dark secret: the Night Class is full of vampires.

Cross Academy is attended by two groups of students: the Day Class and the Night Class. At twilight, when the students of the Day Class return to their dorm, they cross paths with the Night Class on their way to school. Yuki Cross and Zero Kiryu are the Guardians of the school, protecting the Day Class from the Academy's dark secret: the Night Class is full of vampires

Zero is suspected of killing Shizuka Hio, the pureblood vampire who murdered his family. Incensed, the vampire senate sends assassins to Cross Academy to execute him. Will the Night Class intervene, or will Kaname let Zero take the fall?

Matsuri Hino burst onto the manga scene with her title “Kono Yume ga Sametara” (“When This Dream Is Over”), which was published in “LaLa DX”?magazine. Hino was a manga artist a mere nine months after she decided to become one. With the success of her popular series “Captive Hearts” and “MeruPuri”, Hino has established herself as a major player in the world of shojo manga. “Vampire Knight” is currently serialized in “LaLa” magazine.