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Glia and Inflammation in Neurodegenerative Disease

  • Hardcover
Reviews the knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. This book considers the changing role of inflammation with development. It also presents a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
Glia and Inflammation in Neurodegenerative Disease
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Expected delivery Sep 29 – Oct 05
The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brains resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
Introduction; The Central Nervous System and Inflammation: Microglia; The Central Nervous System and Inflammation: Astrocytes; Cell Death Pathways and the Immune Response; Glial-Neuronal Cross-Talk in Neurodegeneration; Inflammation in Stroke; Interactions of Neuroinflammatory and Neurodegenerative Mechanisms in Alzheimer's Disease; Inflammation in Parkinson's Disease; Hypoxic Ishcemic Insults and Inflammation in the Developing Brain; Neurotrama and Inflammation; Anti-inflammatory Treatments for Neurodegeneration; Index.
Pages
275
Publisher
Nova Science Publishers Inc
Year
2007
ISBN-10
1594549842
ISBN-13
9781594549847
Format
Hardcover
Publication Date
2007-02-05
Imprint
Nova Science Publishers Inc
Place of Publication
New York
Country of Publication
United States
Edited by
R.G. Giffard, M. A. Yenari
DEWEY
616.80479
Illustrations
colour illus
Edition
1st
Author
M.a. Yenari
Short Title
GLIA & INFLAMMATION IN NEURODE
Series
Nova Biomedical
Language
English
Media
Book
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