Contact Us Need Help? Call us 1800-987-323
Explore Departments
  Free shipping Australia wide

Protein Chaperones and Protection from Neurodegenerative Diseases

  • Hardcover
* Examines the variety of roles that chaperones play in neurodegenerative diseases such as Huntington s disease and Parkinson s disease. * Caters to the ever-growing, global aging population.
Protein Chaperones and Protection from Neurodegenerative Diseases
$186.21 + free shipping
Ships from United Kingdom
Expected delivery Oct 03 – Oct 10
The intersection of molecular chaperones and neurodegeneration is an intensely studied area because of the potential of manipulating the expression of molecular chaperones to thwart the progression of debilitating diseases. Encompassing contributions from leading experts, <i>Molecular Chaperones and Protection from Neurodegenerative Proteopathies</i> provides an in-depth examination of how protein chaperones are involved in protecting cells from toxic aggregated or misfolded protein states responsible for such diseases as Huntington's and Parkinson's diseases. Addressing the subject from both research and clinical perspectives, the book will appeal to scientists working in these areas of research.
Stephan N. Witt is a Professor in the Department of Biochemistry and Molecular Biology at the Louisiana State University Health Sciences Center in Shreveport, Louisiana. He obtained his PhD in biophysical chemistry from the California Institute of Technology.??Dr. Witt is a member of the editorial board of Cell Stress and Chaperones. He has served on numerous NIH study sections, has authored over forty scientific publications, and edited a book on using yeast as a model for human disease. His research focuses on identifying genes and small molecules that can be used against Parkinson's disease.
Preface. Introduction. Contributors. 1 Intrinsically Disordered Chaperones and Neurodegeneration (Vladimir N. Uversky). 2 Redox Regulation of Protein Misfolding, Synaptic Damage, and Neuronal Loss in Neurodegenerative Diseases (Tomohiro Nakamura and Stuart A. Lipton). 3 Chaperone-Mediated Autophagy and Parkinson s Disease (Marta Martinez-Vicente and Ester Wong). 4 Chaperone and Anti-Chaperone Properties of Synuclein: Implications for Development, Aging, and Neurodegenerative Disease (Makoto Hashimoto, Kazuanri Sekiyama, Akio Sekigawa, and Masayo Fujita). 5 The Ubiquitin Proteasome System in Neurodegenerative Diseases: More than the Usual Suspects (Anne Bertolotti). 6 Regulation of the Polyglutamine Androgen Receptor by the Hsp90/Hsp70-Based Chaperone Machinery (Andrew P. Lieberman and William B. Pratt). 7 Amyloid Remodeling by Hsp104 (James Shorter). 8 Chaperone-Dependent Amyloid Assembly and Prion Toxicity (Daniel W. Summers, Katie J. Wolfe, and Douglas M. Cyr). 9 Modulation of Amyloid Propagation in Yeast by Hsp70 and its Regulators and Chaperone Partners (Daniel C. Masison). 10 ALS and the Copper Chaperone CCS (Marjatta Son and Jeffrey L. Elliott). 11 Emerging Area: TorsinA, a Novel ATP-Dependent Factor Linked to Dystonia (Michal Zolkiewski and Hui-Chuan Wu). 12 Therapeutics: Harnessing the Power of Molecular and Pharmacological Chaperones (David S. Gross, Ronald L. Klein and Stephan N. Witt). Index.
Author
Stephan N. Witt, Vladimir Uversky
Short Title
PROTEIN CHAPERONES & PROTECTIO
Publisher
John Wiley & Sons
Series
Wiley Series in Protein and Peptide Science
Language
English
ISBN-10
0470569077
ISBN-13
9780470569078
Media
Book
Format
Hardcover
DEWEY
612.8
Series Number
7
Year
2011
Imprint
Wiley-Blackwell
Subtitle
On Kant's Philosophy of Material Nature
Edited by
Stephan N. Witt
Publication Date
2011-08-19
Illustrations
Illustrations
Pages
427
Audience
Professional and Scholarly
Edition
1st
Place of Publication
Hoboken
Country of Publication
United States
FREE DELIVERY

Delivery is free to any Australian address. No matter where your item is going.

SECURE PAYMENT

We use 100% PCI DSS compliant payment services. That means your payment information is always protected, and never gets seen by anyone.

30 DAY RETURN POLICY

Return any item within 30 days of delivery. It doesn’t matter why you want to return your item, you can free of charge!