Organic Laboratory Experiments of the Future

Bruce Lipshutz is a Distinguished Professor of Chemistry at UC Santa Barbara (UCSB). He received his Ph.D. at Yale in 1977, and then became an American Cancer Society Postdoctoral Research Fellow at Harvard University, working with Nobel Laureate E. J. Corey. After two years, he joined UCSB as an Assistant Professor, becoming a full Professor of Chemistry in 1989. His research group shifted from traditional organic synthesis to sustainable chemistry, focusing on water as a medium. The Lipshutz research group develops new technologies in green chemistry, aiming to eliminate organic solvents from organic reactions through “designer” surfactants within aqueous micellar catalysis. This involves nanoparticles forming nanoreactors in water for transition metal-catalyzed cross-couplings and other reactions under mild conditions. The group also develops catalysts for Pd- and other transition metal-catalyzed reactions for C-C, C-N, and C-H bond formation at the parts per million level of the metal. These chemo-catalysis technologies are being merged with enzymatic processes, known as “chemoenzymatic catalysis,” for tandem, 1-pot reactions in water. He has received awards in traditional and green chemistry, including the EPA’s Presidential Green Chemistry Challenge Award, the American Chemical Society’s Green Chemistry Institute’s Peter Dunn Award, and the H. C. Brown Award for Creativity in Organic Synthesis.

Hubert is a native of Poland, where he received his B.S./M.S. in Chemistry at Wrocław University of Technology in 2006. He began graduate studies at Vanderbilt with Prof. Jeffrey N. Johnston, developing an α-diazo imide reagent for the Brønsted acid catalyzed syn-glycolate Mannich reaction. He then used the Bronsted acid-promoted azide-alkene synthesis of vic-amino alcohols to develop a two directional synthesis approach to (+)-zwittermicin A. Hubert was a postdoctoral scholar with Prof. Ned Porter until 2015, investigating the kinetic isotope effect of lipid peroxidation. In 2015, he joined the Chemistry Department at Fresno State as Assistant Professor of Chemistry and was promoted to Associate Professor with tenure in 2021.

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